Segments

PROS:
Barebones simple
Location based updates
It's free

CONS:
Weak design
Shoddy tweet entry
No character counter

PROS:
Ability to adjust number of tweets downloaded
Ability to choose where to store your data cache
It's free

CONS:
It's a memory hog
Can be slow when downloading tweets

PROS:
Great design
Tabs allow filtering
Customizable

CONS:
No controls for number of tweets downloaded
Not free